Thomas Wolkow, PhD

photo of Thomas Wolkow, Ph.D.

Thomas Wolkow, PhD

Chair, Associate Professor
Department of Biology
OCSE B339; laboratory OCSE B403

Education

  • 1998-2003 Postdoctoral Research Fellow, Harvard Medical School, Boston, MA
  • 1993-1998 Ph.D., Molecular Genetics, Purdue University, West Lafayette, IN
  • 1989-1993 B.A., Biology, Mathematics Minor, Lafayette College, Easton, PA

Organizations

Member and Preceptor of the University of Colorado Cancer Center: http://www.ucdenver.edu/academics/colleges/medicalschool/centers/cancercenter/Pages/CancerCenter.aspx

Research Interests

Tom Wolkow is an Associate Professor of Biology at UCCS with research experience in different areas of mycology. He earned his Bachelor's degree from Lafayette College (Easton, PA) where he worked in the lab of Dr. Shyamal Majumdar using electron microscopy to catalog the fungal diversity of local rivers and streams. In graduate school at Purdue University (West Lafayette, IN), he joined Dr. John Hamer's lab to study the molecular mechanisms of cellular development using the filamentous fungus, Aspergillus nidulans. After finishing his PhD in 1998, he joined Dr. Tamar Enoch's lab at Harvard Medical School (Boston, MA) to study genomic stability pathways using the fission yeast, Schizosaccharomyces pombe. He is currently using fission yeast to study how eukaryotic cells detect and respond to different environmental stresses.

Selected Publications

  • Spindle-pole-body separation following interphase microtubule damage," Journal of Cell Science, 123(Pt 9):1537-45.
  • Baschal, E., Chen, J., Elliott, L., Herring, M., Verde, S. and T. Wolkow (2006). The fission yeast DNA structure checkpoint protein Rad26 accumulates in the cytoplasm following microtubule destabilization. BMC Cell Biology. 7:32
  • Wolkow, T. and T. Enoch (2003). Fission yeast Rad26 responds to DNA damage independently of Rad3. BMC Genetics. 4:6
  • Wolkow, T. and T. Enoch (2002). Rad26 is a regulatory subunit of the Rad3 checkpoint kinase in fission yeast. Molecular Biology of the Cell. 13: 480-492
  • Wolkow, T., Mirabito, P.M., Venkatram, S. and J.E. Hamer (2000). Hypomorphic bimAAPC3 alleles cause errors in chromosome metabolism that activate the DNA damage checkpoint blocking cytokinesis in Aspergillus nidulans. Genetics 154:167-179

Wolkow's publications through PubMed

Courses Taught

  • BIOL 3020 Cell Biology
  • BIOL 3610 Developmental Biology
  • BIOL 4670 Applied Molecular Genetics